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ARN-21934

HY-137466
MedChem Express
CAS Number2230854-93-8
DownloadMSDS
Product group Chemicals
Estimated Purity98.08
Molecular Weight360.46
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Overview

  • Supplier
    MedChem Express
  • Product Name
    ARN-21934 [2230854-93-8]
  • Delivery Days Customer
    10
  • CAS Number
    2230854-93-8
  • Certification
    Research Use Only
  • Estimated Purity
    98.08
  • Molecular Formula
    C21H24N6
  • Molecular Weight
    360.46
  • Scientific Description
    ARN-21934 is a potent, highly selective, blood-brain barrier (BBB) penetrant inhibitor for human topoisomerase II alpha over beta. ARN-21934 inhibits DNA relaxation with an IC 50 of 2 microM as compared to the anticancer agent Etoposide (IC 50 =120 microM). ARN-21934 exhibits a favorable in vivo pharmacokinetic profile and is a promising lead compound for anticancer research [1] .
  • SMILES
    NC1CC2=C(NC3=CC=C(N(C)C)C=C3)N=C(C4=CC=NC=C4)N=C2CC1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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