ARNT2 antibody [N2C1], Internal

GeneTex

ARNT2 antibody [N2C1], Internal

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

0.47 mg/ml

Unconjugated

ARNT2

aryl hydrocarbon receptor nuclear translocator 2

ARNT protein 2; aryl hydrocarbon receptor nuclear translocator 2; bHLHe1; class E basic helix-loop-helix protein 1; WEDAS

Rabbit

IgG

Aryl hydrocarbon receptor nuclear translocator 2

This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq]

Mouse

-20°C or -80°C,2°C to 8°C

12352203