ARP-100

MedChem Express

ARP-100 [704888-90-4]

10

704888-90-4

Research Use Only

99.0

C17H20N2O5S

364.42

ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with S1 pocket of MMP-2 and shows anti-invasive properties in an in vitro model of invasion on matrigel. ARP-100 shows the less inhibitory activity towards MMP-1 (>50 microM), MMP-3 (4.5 microM), MMP-7 (>50 microM), and MMP-9 (0.2 microM)[1][2].

O=C(NO)CN(S(=O)(C1=CC=C(C2=CC=CC=C2)C=C1)=O)OC(C)C

-20°C

12352200