Bio-Connect

ARQ 069

HY-101544
MedChem Express
CAS Number1314021-57-2
Product group Chemicals
Molecular Weight273.33
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    MedChem Express
  • Product Name
    ARQ 069 [1314021-57-2]
  • Delivery Days Customer
    10
  • CAS Number
    1314021-57-2
  • Certification
    Research Use Only
  • Molecular Formula
    C18H15N3
  • Molecular Weight
    273.33
  • Scientific Description
    ARQ 069, an analog of ARQ 523, inhibits FGFR in an enantiospecific manner. ARQ 069 targets the unphosphorylated, inactive forms of FGFR1/FGFR2 kinases ( IC 50 s of 0.84 microM and 1.23 microM, respectively). ARQ 069 inhibits FGFR1/FGFR2 autophosphorylation ( IC 50 s of 2.8 and 1.9 microM, respectively) through a mechanism in a non-ATP competitive dependent manner [1] .
  • SMILES
    NC1=NC=C2C[C@@H](C3=CC=CC=C3)C4=CC=CC=C4C2=N1
  • UNSPSC
    12352200