ARQ 069
HY-101544
CAS Number1314021-57-2
Product group Chemicals
Molecular Weight273.33
Overview
- SupplierMedChem Express
- Product NameARQ 069 [1314021-57-2]
- Delivery Days Customer10
- CAS Number1314021-57-2
- CertificationResearch Use Only
- Molecular FormulaC18H15N3
- Molecular Weight273.33
- Scientific DescriptionARQ 069, an analog of ARQ 523, inhibits FGFR in an enantiospecific manner. ARQ 069 targets the unphosphorylated, inactive forms of FGFR1/FGFR2 kinases ( IC 50 s of 0.84 microM and 1.23 microM, respectively). ARQ 069 inhibits FGFR1/FGFR2 autophosphorylation ( IC 50 s of 2.8 and 1.9 microM, respectively) through a mechanism in a non-ATP competitive dependent manner [1] .
- SMILESNC1=NC=C2C[C@@H](C3=CC=CC=C3)C4=CC=CC=C4C2=N1
- UNSPSC12352200