ARQ 621

MedChem Express

ARQ 621 [1095253-39-6]

10

1095253-39-6

Research Use Only

99.0

C28H24Cl2FN5O2

552.43

ARQ 621 is an allosteric, potent and selective inhibitor of Eg5 , a microtubule-based ATPase motor protein involved in cell division. Anti-tumor activity [1] . ARQ 621 is a kinesin inhibitor [2] . ARQ 621 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

O=C(N(CCCN)[C@@H](C(N1NC2=CC=CC=C2)=NC3=C(C=CC(Cl)=C3)C1=O)CC#C)C4=CC=CC(Cl)=C4F

-20°C

12352200