Western blot analysis of extracts of various cell lines using ARRB2 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using ARRB2 Polyclonal Antibody at dilution of 1:1000.
ARRB2 Polyclonal Antibody
E-AB-60229
Product group Antibodies
Overview
- SupplierElabscience
- Product NameARRB2 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionMembers of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- UNSPSC12352203