Artemin antibody

GeneTex

Artemin antibody

9

Reacts with the N terminus of Artemin.

Western blot - Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.

Western Blot, ELISA

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

Liquid

ARTN

artemin

ART; artemin; ENOVIN; EVN; NBN; neublastin

Rabbit

IgG

Artemin

This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma. [provided by RefSeq, Aug 2016]

Human

-20°C or -80°C,2°C to 8°C

12352203