Articaine (hydrochloride) [23964-57-0]
HY-B0516
CAS Number23964-57-0
Product group Chemicals
Estimated Purity99.38
Molecular Weight320.84
Overview
- SupplierMedChem Express
- Product NameArticaine (hydrochloride) [23964-57-0]
- Delivery Days Customer5
- CAS Number23964-57-0
- CertificationResearch Use Only
- Estimated Purity99.38
- Hazard Informationh315, h319, h335
- Molecular FormulaC13H21ClN2O3S
- Molecular Weight320.84
- Scientific DescriptionArticaine (Hoe-045) hydrochloride is a selective inhibitor of voltage-gated sodium channels (such as rNav1.4, hNav1.7, and rNav1.8), with an IC50 of 15.8 microM for open-state Na+ channels, and IC50 of 40.6 microM and 378 microM for inactivated and resting-state Na+ channels, respectively. Articaine hydrochloride exerts local anesthetic activity by inhibiting Na+ influx to block nerve impulse conduction, and can also inhibit NF-kappaB activation and NLRP3 inflammasome pathways, exhibiting anti-inflammatory function. Articaine hydrochloride can be used in the study of dental local anesthesia and inflammatory-related diseases (such as acute kidney injury)[1][2][3].
- SMILESO=C(C(C)NCCC)NC(C(C)=CS1)=C1C(OC)=O.Cl
- Storage Instruction2°C to 8°C
- UNSPSC12352200
MSDS
Related products
Product group Chemicals
Articaine hydrochlorideORB762797
CAS Number23964-57-0
Estimated Purity>98%
- SizePrice
Product group Chemicals
CAS Number23964-57-0
Molecular Weight320.84 g/mol
- SizePrice
Product group Chemicals
CAS Number23964-57-0
Estimated Purity>98%
Molecular Weight284.4 . 36.5
- SizePrice
Product group Chemicals
CAS Number23964-57-0
- SizePrice
![Articaine hydrochloride [23964-57-0] [23964-57-0]](https://www.targetmol.com/group3/M00/02/E4/CgoaEGY7QPiEUtAKAAAAAJZJ5jY658.png)
Product group Chemicals
CAS Number23964-57-0
Estimated Purity≥98%
Molecular Weight320.84
- SizePrice