Artobiloxanthone

MedChem Express

Artobiloxanthone

5

Research Use Only

C25H22O7

434.44

Artobiloxanthone (Compound AA3) exhibits antitumor activity, particularly against oral squamous cell carcinoma (OSCC). Artobiloxanthone inhibits Akt/mTOR pathway and STAT3 pathway, inhibits proliferation of SAS and T.Tn (with IC50 of 11 and 22 microM), and inhibits the cancer cell migration. Artobiloxanthone arrests cell cycle at S phase, and induces apoptosis in OSCC cells through activation of caspase 3/9[1].

C=C(C1CC2=C(C3=C(C=C(C(O)=C31)O)O)OC4=C5C=CC(C)(OC5=CC(O)=C4C2=O)C)C

12352200