AS-1669058 [1395553-32-8]

MedChem Express

AS-1669058 [1395553-32-8]

5

1395553-32-8

Research Use Only

C20H17BrF2N4O5

511.27

AS-1669058 is a GPR119 agonist and a potential inhibitor of type 2 diabetes. AS-1669058 induces insulin secretion in response to high blood glucose levels in vitro and in vivo and increases insulin promoter activity. In animal studies, AS-1669058 improved glucose tolerance and reduced blood glucose levels in db/db mice[1].

CC1=CC(NCCC2=C[N+]([O-])=CC=C2)=NC(C3=CC(F)=C(Br)C=C3F)=N1.O=C(O)C(O)=O

12352200