AS-1669058 (free base) [1395553-31-7]

MedChem Express

AS-1669058 (free base) [1395553-31-7]

5

1395553-31-7

Research Use Only

C18H15BrF2N4O

421.24

AS-1669058 free base is a GPR119 agonist and a potential inhibitor of type 2 diabetes. AS-1669058 free base induces insulin secretion induced by high blood glucose levels in vitro and in vivo and increases insulin promoter activity. In animal studies, AS-1669058 free base improved glucose tolerance and reduced blood glucose levels in db/db mice.

[O-][N+]1=CC=CC(CCNC2=NC(C3=CC(F)=C(Br)C=C3F)=NC(C)=C2)=C1

12352200