AS19

MedChem Express

AS19 [1000578-26-6]

5

1000578-26-6

Research Use Only

99.85

C18H25N3

283.41

AS19 is a potent, selective 5-HT 7 receptor agonist with an IC 50 value of 0.83 nM and a K i of 0.6 nM. AS19 is selective for 5-HT 7 over 5-HT 1A , 5-HT 1B , 5-HT 1D , and 5-HT 5A receptors ( K i s = 89.7 nM, 490 nM, 6.6 nM and 98.5 nM, respectively). AS19 enhances memory consolidation and reverses Scopolamine- or Dizocilpine-induced amnesia [1] [2] [3] .

CC1=C(C2=CC=CC3=C2CC[C@H](N(C)C)C3)C(C)=NN1C

-20°C

12352200