
Western Blot Positive WB detected in: Hela whole cell lysate, Rat stomach tissue All lanes: ASAH2 antibody at 3microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 86, 82 kDa Observed band size: 86 kDa
ASAH2 Antibody
CSB-PA002170EA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
TargetASAH2
Overview
- SupplierCusabio
- Product NameASAH2 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID56624
- Target nameASAH2
- Target descriptionN-acylsphingosine amidohydrolase 2
- Target synonymsacylsphingosine deacylase 2; BCDase; HNAC1; LCDase; mitochondrial ceramidase; N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2; NCDase; N-CDase; neutral ceramidase; neutral/alkaline ceramidase; non-lysosomal ceramidase
- HostRabbit
- IsotypeIgG
- Protein IDQ9NR71
- Protein NameNeutral ceramidase
- Scientific DescriptionHydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203