ASCC1 Polyclonal Antibody

Elabscience

ASCC1 Polyclonal Antibody

12

ImmunoHistoChemistry

ELISA IHC

Research Use Only

Polyclonal

0.3 mg/ml

Unconjugated

ASCC1

activating signal cointegrator 1 complex subunit 1

ASC1p50, CGI-18, SMABF2, p50, activating signal cointegrator 1 complex subunit 1, ASC-1 complex subunit P50, trip4 complex subunit p50

Rabbit

IgG

Activating signal cointegrator 1 complex subunit 1

This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

-20°C

41116161