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ASGPR1 antibody [N1C3]

GTX122674
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetASGR1
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Overview

  • Supplier
    GeneTex
  • Product Name
    ASGPR1 antibody [N1C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.3 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID432
  • Target name
    ASGR1
  • Target description
    asialoglycoprotein receptor 1
  • Target synonyms
    ASGPR; ASGPR1; asialoglycoprotein receptor 1; CLEC4H1; C-type lectin domain family 4 member H1; hepatic lectin H1; HL-1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP07306
  • Protein Name
    Asialoglycoprotein receptor 1
  • Scientific Description
    Partially deglycosylated plasma glycoproteins and immunoglobulin IgA2 allotypes are efficiently and specifically removed from circulation by a receptor-mediated process. The asialoglycoprotein receptor binds to desialylated (galactosyl-terminal) glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociate. Then the receptor is recycled back to the cell surface and the ligand is transported to the lysosomes for degradation. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Protein and miRNA profile of circulating extracellular vesicles in patients with primary sclerosing cholangitis. Povero D et al., 2022 Feb 22, Sci Rep
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  • Protein Composition of Circulating Extracellular Vesicles Immediately Changed by Particular Short Time of High-Intensity Interval Training Exercise. Kobayashi Y et al., 2021, Front Physiol
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  • Circulating extracellular vesicles with specific proteome and liver microRNAs are potential biomarkers for liver injury in experimental fatty liver disease. Povero D et al., 2014, PLoS One
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  • Intracellular delivery of cytochrome c by galactosylated albumin to hepatocarcinoma cells. Yeh TH et al., 2014 Jul, J Drug Target
    Read more
  • Effect of high glucose on secreted proteome in cultured retinal pigmented epithelium cells: its possible relevance to clinical diabetic retinopathy. Chen YH et al., 2012 Dec 21, J Proteomics
    Read more