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Asiatic acid (Standard) [464-92-6]

HY-N0194R
MedChem Express
CAS Number464-92-6
Product group Chemicals
Molecular Weight488.70
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Asiatic acid (Standard) [464-92-6]
  • Delivery Days Customer
    5
  • CAS Number
    464-92-6
  • Category Supplier
    CHEMICAL,detergents_surfactants
  • Certification
    Research Use Only
  • Molecular Weight
    488.70
  • Scientific Description
    Asiatic acid (Standard) is the analytical standard of Asiatic acid. This product is intended for research and analytical applications. Asiatic acid, a pentacyclic triterpene found in Centella asiatica (Centella asiatica), has anticancer activity. Asiatic acid induces apoptosis in melanoma cells and has barrier protective effects on human aortic endothelial cells (HAEC). Asiatic acid also has anti-inflammatory activity and inhibits tumor necrosis factor (TNF)-alpha-induced endothelial barrier dysfunction. Asiatic acid also inhibits NLRP3 inflammasome activation and NF-kappaB pathway, effectively inhibits inflammation in rats, and has neuroprotective effects in rat spinal cord injury (SCI) model[1][2][3][4][5].
  • SMILES
    C[C@@]1(CO)[C@@H](O)[C@H](O)C[C@]2(C)[C@@]3([H])CC=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@@](C(O)=O)5CC[C@](C)4[C@@](C)3CC[C@@]12[H]
  • UNSPSC
    12352211