Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA002212LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA002212LA01HU at dilution of 1:100
ASIP Antibody
CSB-PA002212LA01HU
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
Product group Antibodies
TargetASIP
Overview
- SupplierCusabio
- Product NameASIP Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID434
- Target nameASIP
- Target descriptionagouti signaling protein
- Target synonymsagouti signaling protein, nonagouti homolog; agouti switch protein; agouti-signaling protein; AGSW; AGTI; AGTIL; ASP; nonagouti homolog; SHEP9
- HostRabbit
- IsotypeIgG
- Protein IDP42127
- Protein NameAgouti-signaling protein
- Scientific DescriptionInvolved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). In higher primates, agouti may affect the quality of hair pigmentation rather than its pattern of deposition. Could well play a role in neuroendocrine aspects of melanocortin action. May have some functional role in regulating the lipid metabolism with adipocytes.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203
