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Aspartoacylase antibody [N1C3-2]

GTX113389
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetASPA
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Overview

  • Supplier
    GeneTex
  • Product Name
    Aspartoacylase antibody [N1C3-2]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.33 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID443
  • Target name
    ASPA
  • Target description
    aspartoacylase
  • Target synonyms
    ACY2; ACY-2; aminoacylase 2; ASP; aspartoacylase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP45381
  • Protein Name
    Aspartoacylase
  • Scientific Description
    This gene encodes an enzyme that catalyzes the conversion of N-acetyl_L-aspartic acid (NAA) to aspartate and acetate. NAA is abundant in the brain where hydrolysis by aspartoacylase is thought to help maintain white matter. This protein is an NAA scavenger in other tissues. Mutations in this gene cause Canavan disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • High-efficiency pharmacogenetic ablation of oligodendrocyte progenitor cells in the adult mouse CNS.
    Read more
  • Insights into the mechanism of oligodendrocyte protection and remyelination enhancement by the integrated stress response.
    Read more
  • Age and Alzheimers Disease-Related Oligodendrocyte Changes in Hippocampal Subregions. DeFlitch L et al., 2022, Front Cell Neurosci
    Read more
  • Myelination Deficits in the Auditory Brainstem of a Mouse Model of Fragile X Syndrome. Lucas A et al., 2021, Front Neurosci
    Read more
  • Prenatal overexpression of platelet-derived growth factor receptor A results in central nervous system hypomyelination. Cardona HJ et al., 2021 Oct, Brain Behav
    Read more
  • Prolonging the integrated stress response enhances CNS remyelination in an inflammatory environment. Chen Y et al., 2021 Mar 23, Elife
    Read more
  • Ex vivo MR microscopy of a human brain with multiple sclerosis: Visualizing individual cells in tissue using intrinsic iron. Nair G et al., 2020 Dec, Neuroimage
    Read more
  • Remyelination alters the pattern of myelin in the cerebral cortex. Orthmann-Murphy J et al., 2020 May 27, Elife
    Read more
  • GDE2-Dependent Activation of Canonical Wnt Signaling in Neurons Regulates Oligodendrocyte Maturation. Choi BR et al., 2020 May 5, Cell Rep
    Read more
  • Oligodendrocytes Support Neuronal Glutamatergic Transmission via Expression of Glutamine Synthetase. Xin W et al., 2019 May 21, Cell Rep
    Read more

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