Aspartoacylase antibody [N1C3-2]
GTX113389
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Monkey, Mouse
TargetASPA
Overview
- SupplierGeneTex
- Product NameAspartoacylase antibody [N1C3-2]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.33 mg/ml
- ConjugateUnconjugated
- Gene ID443
- Target nameASPA
- Target descriptionaspartoacylase
- Target synonymsACY2; ACY-2; aminoacylase 2; ASP; aspartoacylase
- HostRabbit
- IsotypeIgG
- Protein IDP45381
- Protein NameAspartoacylase
- Scientific DescriptionThis gene encodes an enzyme that catalyzes the conversion of N-acetyl_L-aspartic acid (NAA) to aspartate and acetate. NAA is abundant in the brain where hydrolysis by aspartoacylase is thought to help maintain white matter. This protein is an NAA scavenger in other tissues. Mutations in this gene cause Canavan disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
- ReactivityHuman, Monkey, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- High-efficiency pharmacogenetic ablation of oligodendrocyte progenitor cells in the adult mouse CNS.Read more
- Insights into the mechanism of oligodendrocyte protection and remyelination enhancement by the integrated stress response.Read more
- Age and Alzheimers Disease-Related Oligodendrocyte Changes in Hippocampal Subregions. DeFlitch L et al., 2022, Front Cell NeurosciRead more
- Myelination Deficits in the Auditory Brainstem of a Mouse Model of Fragile X Syndrome. Lucas A et al., 2021, Front NeurosciRead more
- Prenatal overexpression of platelet-derived growth factor receptor A results in central nervous system hypomyelination. Cardona HJ et al., 2021 Oct, Brain BehavRead more
- Prolonging the integrated stress response enhances CNS remyelination in an inflammatory environment. Chen Y et al., 2021 Mar 23, ElifeRead more
- Ex vivo MR microscopy of a human brain with multiple sclerosis: Visualizing individual cells in tissue using intrinsic iron. Nair G et al., 2020 Dec, NeuroimageRead more
- Remyelination alters the pattern of myelin in the cerebral cortex. Orthmann-Murphy J et al., 2020 May 27, ElifeRead more
- GDE2-Dependent Activation of Canonical Wnt Signaling in Neurons Regulates Oligodendrocyte Maturation. Choi BR et al., 2020 May 5, Cell RepRead more
- Oligodendrocytes Support Neuronal Glutamatergic Transmission via Expression of Glutamine Synthetase. Xin W et al., 2019 May 21, Cell RepRead more