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ASPH, Human (His-SUMO)

Name: ASPH, Human (His-SUMO)
SKU: HY-P72092_M09
Availability: BackOrder

HY-P72092

Protein IDQ12797

Product group Proteins / Signaling Molecules

Overview

Supplier
MedChem Express
Product Name
ASPH, Human (His-SUMO)
Delivery Days Customer
10
Certification
Research Use Only
Gene ID444
Target name
ASPH
Target description
aspartate beta-hydroxylase
Target synonyms
AAH, BAH, CASQ2BP1, FDLAB, HAAH, JCTN, junctin, aspartyl/asparaginyl beta-hydroxylase, A beta H-J-J, ASP beta-hydroxylase, cardiac junctin, humbug, junctate, peptide-aspartate beta-dioxygenase
Protein IDQ12797
Protein Name
Aspartyl/asparaginyl beta-hydroxylase
Scientific Description
ASPH protein phosphorylates SPRTN, facilitating its chromatin recruitment and decreasing replication stress. ASPH activates the G2/M checkpoint by phosphorylating and inhibiting PABIR1/FAM122A, leading to serine/threonine-protein phosphatase 2A-mediated dephosphorylation and stabilization of WEE1 levels and activity. ASPH Protein, Human (His-SUMO) is the recombinant human-derived ASPH protein, expressed by E. coli, with N-6*His, N-SUMO labeled tag.
UNSPSC
41116100