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Astegolimab [2173054-79-8]

HY-P99444
MedChem Express
Product group Antibodies
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Astegolimab [2173054-79-8]
  • Delivery Days Customer
    10
  • CAS Number
    2173054-79-8
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Estimated Purity
    99.00
  • Scientific Description
    Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody. Astegolimab blocks IL-33 signaling by targeting the IL-33 receptor ST2. Astegolimab reduces p53 expression, mitigates IL33-upregulated SASP factors such as IL1alpha, IL6 and MCP1. Astegolimab mitigates IL33-increased p-p65/p65 ratio. Astegolimab blocks CM-induced neutrophil extracellular trap (NET) formation. Astegolimab is used in chronic obstructive pulmonary disease (COPD) and myocardial research[1][2][3].
  • Storage Instruction
    -80°C
  • UNSPSC
    41116161

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