Asundexian

MedChem Express

Asundexian [2064121-65-7]

10

2064121-65-7

Research Use Only

99.80

C26H21ClF4N6O4

592.93

Asundexian (BAY 2433334) is an orally active coagulation factor Xia (FXIa) inhibitor. Asundexian binds directly, potently, and reversibly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC 50 of 1 nM [1] .

COC(C(C1=C(N2C=C(N=N2)C(F)(F)F)C=CC(Cl)=C1)=C3)=CN([C@@H](CC)C(NC4=CC(F)=C(C=C4)C(N)=O)=O)C3=O

-20°C

12352200