AT-533 [908112-37-8]

TargetMol Chemicals

AT-533 [908112-37-8]

4

Chemical

Research Use Only

AT-533

99.54%

C23H30N4O3

410.51

AT-533 is a potent inhibitor of Hsp90 and HSV. AT-533 blocks the HIF-1alpha/VEGF/VEGFR-2 signaling pathway, leading to suppress tumor growth and angiogenesis. AT-533 also inhibits the activation of the downstream pathways, including Erk1/2, FAK, Akt/mTOR/p70S6K,. AT-533 inhibits the cell migration, invasion, and the tube formation of human umbilical vein endothelial cells (HUVECs).

3 years

Cc1nn(c2CC(C)(C)CC(=O)c12)-c1ccc(C(N)=O)c(N[C@H]2CC[C@H](O)CC2)c1

-20°C

12352200