AT-56 [162640-98-4]

MedChem Express

AT-56 [162640-98-4]

5

162640-98-4

Research Use Only

98%

C25H27N5

397.52

AT-56 is a potent, selective and orally active inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS), with an IC50 of 95 microM and Ki of 75 microM. AT-56 could selectively suppress the drowsiness or pain reaction mediated by L-PGDS-catalyzed PGD2.

N1(CCCCC2=NNN=N2)CC/C(CC1)=C3C4=CC=CC=C4C=CC5=CC=CC=C/35

-20°C,-80°C

12352200