AT-56

MedChem Express

AT-56 [162640-98-4]

10

162640-98-4

98.42

C25H27N5

397.52

AT-56 is a potent, selective and orally active inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS) , with an IC 50 of 95 microM and K i of 75 microM. AT-56 could selectively suppress the drowsiness or pain reaction mediated by L-PGDS -catalyzed PGD 2 [1] .

N1(CCCCC2=NNN=N2)CC/C(CC1)=C3C4=CC=CC=C4C=CC5=CC=CC=C/35

-20°C

12352200