AT2R antagonist 1 [2709031-17-2]

MedChem Express

AT2R antagonist 1 [2709031-17-2]

10

2709031-17-2

Research Use Only

C23H30N4O4S2

490.64

AT2R antagonist 1 (compound 21) is a potent and high selective AT2R (angiotensin II AT2 receptor) ligand. AT2R antagonist 1 exhibits a fair AT2R affinity, with a Ki of 29 nM. AT2R antagonist 1 also inhibits common agent-metabolizing CYP enzymes. AT2R antagonist 1 shows high stability in human, rat and mouse liver microsomes[1].

COC(NS(=O)(C1=C(N=C(S1)CC(C)C)C2=CC=C(C=C2)CN3C=CN=C3C(C)(C)C)=O)=O

12131703