Western Blot Positive WB detected in: U87 whole cell lysate All lanes: ATAT1 antibody at 1 : 1000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 45, 46, 47, 38, 37, 36, 34 kDa Observed band size: 47 kDa
Western Blot Positive WB detected in: U87 whole cell lysate All lanes: ATAT1 antibody at 1 : 1000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 45, 46, 47, 38, 37, 36, 34 kDa Observed band size: 47 kDa
ATAT1 Antibody
CSB-PA725542LA01HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetATAT1
Overview
- SupplierCusabio
- Product NameATAT1 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID79969
- Target nameATAT1
- Target descriptionalpha tubulin acetyltransferase 1
- Target synonymsC6orf134, MEC17, Nbla00487, TAT, alpha-TAT, alpha-TAT1, alpha-tubulin N-acetyltransferase 1, acetyltransferase mec-17 homolog
- HostRabbit
- IsotypeIgG
- Protein IDQ5SQI0
- Protein NameAlpha-tubulin N-acetyltransferase 1
- Scientific DescriptionSpecifically acetylates Lys-40 in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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