Atazanavir

MedChem Express

Atazanavir [198904-31-3]

10

198904-31-3

Research Use Only

99.86

C38H52N6O7

704.86

Atazanavir (BMS-232632) is a highly selective and orally active HIV-1 protease inhibitor . Atazanavir is a substrate and inhibitor of CYP3A4 , and an inhibitor of P-glycoprotein (P-gp) . Atazanavir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 3.49 microM. Atazanavir inhibits cardiac fibrosis, hyperlipidemia and induces malignant glioma death [1] [2] [3] [4] [5] [6] [7] [8] .

O=C(OC)N[C@@H](C(C)(C)C)C(NN(CC1=CC=C(C2=NC=CC=C2)C=C1)C[C@H](O)[C@H](CC3=CC=CC=C3)NC([C@H](C(C)(C)C)NC(OC)=O)=O)=O

-20°C

12352200