ATF6B antibody

GeneTex

ATF6B antibody

9

WB: 1:500~1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

Unconjugated

ATF6B

activating transcription factor 6 beta

ATF6beta, CREB-RP, CREBL1, G13, cyclic AMP-dependent transcription factor ATF-6 beta, Creb-related protein, cAMP response element-binding protein-related protein, cAMP-dependent transcription factor ATF-6 beta, cAMP-responsive element-binding protein-like 1, protein G13

Rabbit

IgG

Cyclic AMP-dependent transcription factor ATF-6 beta

The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

-20°C or -80°C,2°C to 8°C

12352203