Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA002279ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA002279ESR2HU at dilution of 1:100
ATF7 Antibody
CSB-PA002279ESR2HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetATF7
Overview
- SupplierCusabio
- Product NameATF7 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID11016
- Target nameATF7
- Target descriptionactivating transcription factor 7
- Target synonymsATFA; cyclic AMP-dependent transcription factor ATF-7; transcription factor ATF-A
- HostRabbit
- IsotypeIgG
- Protein IDP17544
- Protein NameCyclic AMP-dependent transcription factor ATF-7
- Scientific DescriptionPlays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5\\\-GTGACGT[AG][AG]-3\\\), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family. Isoform 4/ATF-A0 acts as a dominant repressor of the E-selectin/NF-ELAM1/delta-A promoter. Isoform 5/ATF-4 acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203