ATP (Standard)

MedChem Express

ATP (Standard) [56-65-5]

999

56-65-5

Research Use Only

C10H16N5O13P3

507.18

ATP (Standard) is the analytical standard of ATP. This product is intended for research and analytical applications. ATP (Adenosine 5-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation[1][2]. In Vitro: ATP (5 mM; 1 hour) co-treatment with LPS (1 microg/mL) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs[3]. ATP (2 mM; 0.5-24 hours) induces secretion of IL-1beta, KC and MIP-2 from BMDMs in a caspase-1 activation-dependent manner[4]. ATP promotes neutrophil chemotaxis in vitro[4]. In Vivo: ATP (50 mg/kg; i.p.) protects mice against bacterial infection in vivo[4]. ATP induces the secretion of IL-1beta, KC and MIP-2 and neutrophils recruitment in vivo[4].

O=P(O)(O)OP(OP(OC[C@H]1O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@H](O)[C@@H]1O)(O)=O)(O)=O

12352200