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WB analysis of K562 cell tissue lysate in (A) the absence and (B) the presence of blocking peptide using GTX85170 ATP11A antibody. Working concentration : 1 microg/ml
WB analysis of K562 cell tissue lysate in (A) the absence and (B) the presence of blocking peptide using GTX85170 ATP11A antibody. Working concentration : 1 microg/ml
WB analysis of K562 cell tissue lysate in (A) the absence and (B) the presence of blocking peptide using GTX85170 ATP11A antibody. Working concentration : 1 microg/ml

ATP11A antibody

GTX85170
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetATP11A
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Overview

  • Supplier
    GeneTex
  • Product Name
    ATP11A antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1 microg/mL. ICC/IF: 10 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID23250
  • Target name
    ATP11A
  • Target description
    ATPase phospholipid transporting 11A
  • Target synonyms
    ATPase, class VI, type 11A; ATPIH; ATPIS; P4-ATPase flippase complex alpha subunit ATP11A; phospholipid-translocating ATPase; phospholipid-transporting ATPase IH; potential phospholipid-transporting ATPase IH; probable phospholipid-transporting ATPase IH
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP98196
  • Protein Name
    Probable phospholipid-transporting ATPase IH
  • Scientific Description
    ATP11A is a widely expressed integral membrane ATPase. ATP11A is probably phosphorylated in its intermediate state and likely drives the transport of ions such as calcium or other molecules across membranes. While the exact molecule ATP11A transports is unknown, increased expression of ATP11A mRNA has been observed in murine leukemia cells made resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs). Furthermore, overexpression of ATP11A provided protection against the FTI SCH66336 while knockdown of ATP11A via siRNA made cells more sensitive to this drug. Other reports suggest that elevated levels of ATP11A mRNA may also be a predictive marker of metastasis in colorectal cancer patients.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203