ATP8A1 Antibody

Cusabio

ATP8A1 Antibody

20

ImmunoFluorescence, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

ATP8A1

ATPase phospholipid transporting 8A1

ATPASEII, ATPIA, ATPP2, phospholipid-transporting ATPase IA, ATPase II, ATPase class I type 8A member 1, ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1, P4-ATPase flippase complex alpha subunit ATP8A1, aminophospholipid translocase, chromaffin granule ATPase II, probable phospholipid-transporting ATPase IA

Rabbit

IgG

Phospholipid-transporting ATPase IA

Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Acts as aminophospholipid translocase at the plasma membrane in neuronal cells.

Human

-20°C or -80°C

41116161