ATR-IN-15 [2756665-52-6]

MedChem Express

ATR-IN-15 [2756665-52-6]

10

2756665-52-6

Research Use Only

C19H22N8O

378.43

ATR-IN-15 (compound 1) is an orally active and potent ATR kinase inhibitor, with an IC50 of 8 nM. ATR-IN-15 also inhibits human colon tumor cells LoVo, DNA-PK and PI3K, with IC50 values of 47, 663 and 5131 nM, respectively[1].

CC1=NC(C2=CC=NN2)=C3N=C(C=C(N13)N4[C@H](C)COCC4)C5=CC=NN5C

12131703