ATR-IN-18 [2766407-55-8]

MedChem Express

ATR-IN-18 [2766407-55-8]

10

2766407-55-8

Research Use Only

C19H22F3N7O5S

517.48

ATR-IN-18 (compound 2) is an orally active and potent ATR kinase inhibitor, with an IC50 of 0.69 nM. ATR-IN-18 shows antiproliferative activity in LoVo cells, with an IC50 of 37.34 nM. ATR-IN-18 has anti-tumor activity[1].

OC(C(F)(F)F)=O.CS(=O)(N1C2=C(CC1)C(N3[C@@H](COCC3)C)=NC4=C2C=NN4C5=NNC=C5)=O

12131703