Atuzabrutinib

MedChem Express

Atuzabrutinib [1581714-49-9]

10

1581714-49-9

Research Use Only

98.01

C30H30FN7O2

539.60

Atuzabrutinib (SAR 444727) is a potent, selective reversible inhibitor of Btk (Brutons tyrosine kinase) inhibitor. Atuzabrutinib inhibits neutrophil recruitment via inhibition of macrophage antigen-1 signalling[1].

NC1=C2C(N([C@H]3CN(CCC3)C(/C(C#N)=C/C(C)(C)C)=O)N=C2C4=C(C=C(C=C4)OC5=CC=CC=C5)F)=NC=N1

2°C to 8°C

12352200