Atuzabrutinib [1581714-49-9]

TargetMol Chemicals

Atuzabrutinib [1581714-49-9]

16

1581714-49-9

Chemical

Research Use Only

Atuzabrutinib

0.9727

C30H30FN7O2

539.6

Atuzabrutinib (SAR 444727) is a selective Brutons tyrosine kinase (Btk) inhibitor that inhibits intra-neutrophilic neutrophilic granulocytes through inhibition of the adhesion receptor signaling pathway, and can be used to study autoimmune disorders such as arthritis in rheumatoid rodents and pemphigus vulgaris.

3 years

NC1=C2C(N(N=C2C3=C(F)C=C(OC4=CC=CC=C4)C=C3)[C@H]5CN(C(/C(=C/C(C)(C)C)/C#N)=O)CCC5)=NC=N1

-20°C

12352200