ATX inhibitor 18

MedChem Express

ATX inhibitor 18 [2402772-30-7]

10

Research Use Only

C21H17Cl2FN6O

459.30

ATX inhibitor 18 is a potent ATX inhibitor with an IC50 value of 24.2 nM. ATX inhibitor 18 shows antiproliferative activity and anti-fibrosis activity. ATX inhibitor 18 suppresses collagen deposition in TGF-beta-mediated cardiac fibrosis[1].

O=C(N1CCC2=C(C(NC3=CC=C(C(Cl)=C3)F)=NC=N2)C1)N/N=C/C4=CC=C(C=C4)Cl

12131703