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AU-15330

HY-145388
MedChem Express
CAS Number2380274-50-8
DownloadMSDS
Product group Chemicals
Estimated Purity99.89
Molecular Weight755.93
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Overview

  • Supplier
    MedChem Express
  • Product Name
    AU-15330 [2380274-50-8]
  • Delivery Days Customer
    10
  • CAS Number
    2380274-50-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.89
  • Molecular Formula
    C39H49N9O5S
  • Molecular Weight
    755.93
  • Scientific Description
    AU-15330 is a proteolysis-targeting chimera (PROTAC) degrader of the SWI/SNF ATPase subunits, SMARCA2 and SMARCA4 . AU-15330 induces potent inhibition of tumour growth in xenograft models of prostate cancer and synergizes with the AR antagonist enzalutamide. AU-15330 induces disease remission in castration-resistant prostate cancer (CRPC) models without toxicity [1] .
  • SMILES
    O=C(N(C[C@@H]1O)[C@@H](C1)C(N[C@H](C2=CC=C(C(SC=N3)=C3C)C=C2)C)=O)[C@H](C(C)(C)C)NC(CN4CCN(C(C=C(C(C=CC=C5)=C5O)N=N6)=C6N)CC4)=O
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

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