Auristatin E [160800-57-7]

MedChem Express

Auristatin E [160800-57-7]

10

160800-57-7

Research Use Only

99.89

C40H69N5O7

732.01

Auristatin E is a cytotoxic microtubule polymerization inhibitor with potent and selective antitumor activity. Auristatin E is a cytotoxin in antibody-drug conjugates (ADC). Auristatin E inhibits cell division by blocking the polymerisation of tubulin, promising for research in B-cell malignancies. Auristatin E, a synthetic analogue of the Dolastatin 10 (HY-15580), is linear peptides comprised of four amino acids[1][2][3].

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2°C to 8°C

41116133