AURKAIP1 Antibody

Cusabio

AURKAIP1 Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

AURKAIP1

aurora kinase A interacting protein 1

28S ribosomal protein S38, mitochondrial; AIP; AKIP; AURKA-interacting protein; aurora kinase A-interacting protein; aurora-A kinase interacting protein; mitochondrial small ribosomal subunit protein mS38; MRP-S38

Rabbit

IgG

Aurora kinase A-interacting protein

AKIP (AURKA-interacting protein), also known as AURKAIP1 (aurora kinase A interacting protein 1) or AIP, is a 199 amino acid protein that localizes to the nucleus and is ubiquitously expressed, with highest levels present in testis, heart and skeletal muscle. Interacting specifically with ARK-1 (aurora kinase 1), AKIP functions to induce the proteasomal-dependent degradation of ARK-1, thereby acting as a negative regulator of ARK-1 activity. AKIP is encoded by a gene which maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinsons disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

-20°C or -80°C

12352203