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ProductsBack/Aurora kinase-IN-2 [2241914-86-1]

Aurora kinase-IN-2 [2241914-86-1]

HY-150592
MedChem Express
CAS Number2241914-86-1
DownloadMSDS
Product group Chemicals
Molecular Weight435.86
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Aurora kinase-IN-2 [2241914-86-1]
  • Delivery Days Customer
    10
  • CAS Number
    2241914-86-1
  • Certification
    Research Use Only
  • Molecular Formula
    C22H18ClN5O3
  • Molecular Weight
    435.86
  • Scientific Description
    Aurora kinase-IN-2 (compound 12Aj) is a potent Aurora kinase inhibitor with IC50 values of 90 and 152 nM for Aurora A and Aurora B. Aurora kinase-IN-2 arrests cell cycle at G2/M phase by regulating cyclin B1 and cdc2. Aurora kinase-IN-2 can be used for cancer research[1].
  • SMILES
    O=C(NC1=CC=CC(Cl)=C1)C2=CC=C(OC3=NC(C4=C(C)ON=C4C)=CN=C3N)C=C2
  • UNSPSC
    12131703