Aurora kinase-IN-2 [2241914-86-1]
HY-150592
CAS Number2241914-86-1
Product group Chemicals
Molecular Weight435.86
Overview
- SupplierMedChem Express
- Product NameAurora kinase-IN-2 [2241914-86-1]
- Delivery Days Customer10
- CAS Number2241914-86-1
- CertificationResearch Use Only
- Molecular FormulaC22H18ClN5O3
- Molecular Weight435.86
- Scientific DescriptionAurora kinase-IN-2 (compound 12Aj) is a potent Aurora kinase inhibitor with IC50 values of 90 and 152 nM for Aurora A and Aurora B. Aurora kinase-IN-2 arrests cell cycle at G2/M phase by regulating cyclin B1 and cdc2. Aurora kinase-IN-2 can be used for cancer research[1].
- SMILESO=C(NC1=CC=CC(Cl)=C1)C2=CC=C(OC3=NC(C4=C(C)ON=C4C)=CN=C3N)C=C2
- UNSPSC12131703