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Aurora kinase inhibitor-3

HY-112373
MedChem Express
CAS Number879127-16-9
DownloadMSDS
Product group Chemicals
Estimated Purity99.05
Molecular Weight413.40
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Aurora kinase inhibitor-3 [879127-16-9]
  • Delivery Days Customer
    10
  • CAS Number
    879127-16-9
  • Certification
    Research Use Only
  • Estimated Purity
    99.05
  • Molecular Formula
    C21H18F3N5O
  • Molecular Weight
    413.40
  • Scientific Description
    Aurora kinase inhibitor-3 is a strong and selective Aurora A kinase inhibitor with an IC 50 of 42 nM, and weakly inhibits EGFR with an IC 50 of >10 microM. Aurora kinase inhibitor-3 has a binding mode with the cyclopropanecarboxylic acid moiety directed towards the solvent exposed region of the ATP-binding pocket [1] .
  • SMILES
    O=C(C1CC1)NC2=CC=CC(NC3=NC=CC(NC4=CC=CC(C(F)(F)F)=C4)=N3)=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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