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AUY 954 (hydrochloride) [820240-78-6]

HY-119221A
MedChem Express
CAS Number820240-78-6
Product group Chemicals
Molecular Weight491.95
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Overview

  • Supplier
    MedChem Express
  • Product Name
    AUY 954 (hydrochloride) [820240-78-6]
  • Delivery Days Customer
    9
  • CAS Number
    820240-78-6
  • Certification
    Research Use Only
  • Molecular Formula
    C25H21ClF3NO2S
  • Molecular Weight
    491.95
  • Scientific Description
    AUY 954 hydrochloride is a potent and selective sphingosine-1-phosphate (S1P(1)) receptor agonist, exhibiting significant immunomodulatory activity. AUY 954 hydrochloride induces a profound and reversible reduction of circulating lymphocytes upon oral administration. AUY 954 hydrochloride has demonstrated efficacy in prolonging cardiac allograft survival when used in combination with RAD001 in a stringent transplantation model. AUY 954 hydrochloride effectively prevents experimental autoimmune neuritis in rats, showcasing its therapeutic potential in autoimmune conditions.
  • SMILES
    FC(C1=CC(C2=CC3=CC(CNCCC(O)=O)=CC=C3S2)=CC=C1C4=CC=CC=C4)(F)F.Cl
  • UNSPSC
    12352200