AUY 954 (hydrochloride) [820240-78-6]
HY-119221A
CAS Number820240-78-6
Product group Chemicals
Molecular Weight491.95
Overview
- SupplierMedChem Express
- Product NameAUY 954 (hydrochloride) [820240-78-6]
- Delivery Days Customer9
- CAS Number820240-78-6
- CertificationResearch Use Only
- Molecular FormulaC25H21ClF3NO2S
- Molecular Weight491.95
- Scientific DescriptionAUY 954 hydrochloride is a potent and selective sphingosine-1-phosphate (S1P(1)) receptor agonist, exhibiting significant immunomodulatory activity. AUY 954 hydrochloride induces a profound and reversible reduction of circulating lymphocytes upon oral administration. AUY 954 hydrochloride has demonstrated efficacy in prolonging cardiac allograft survival when used in combination with RAD001 in a stringent transplantation model. AUY 954 hydrochloride effectively prevents experimental autoimmune neuritis in rats, showcasing its therapeutic potential in autoimmune conditions.
- SMILESFC(C1=CC(C2=CC3=CC(CNCCC(O)=O)=CC=C3S2)=CC=C1C4=CC=CC=C4)(F)F.Cl
- UNSPSC12352200