More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/AV123 [233605-81-7]

AV123 [233605-81-7]

HY-151369
MedChem Express
CAS Number233605-81-7
DownloadMSDS
Product group Chemicals
Estimated Purity99.60
Molecular Weight234.25
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    MedChem Express
  • Product Name
    AV123 [233605-81-7]
  • Delivery Days Customer
    10
  • CAS Number
    233605-81-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.60
  • Molecular Formula
    C11H14N4O2
  • Molecular Weight
    234.25
  • Scientific Description
    AV123 (compound 12) is a non-cytotoxic RIPK1 inhibitor (IC50=12.12 microM). AV123 blocks the TNF-alpha-induced necroptotic (EC50=1.7 microM) but not the apoptotic cell death. AV123 can be used in the study of necrotic chronic conditions such as ischemia-reperfusion injury of the brain, heart and kidney, inflammatory diseases, neurodegenerative diseases and infectious diseases[1].
  • SMILES
    O=[N+](C1=CC=C2C(NC(NCCCC)=N2)=C1)[O-]
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12131703