Avacopan [1346623-17-3]

TargetMol Chemicals

Avacopan [1346623-17-3]

9

1346623-17-3

Chemical

Research Use Only

Avacopan

99.90%

C33H35F4N3O2

581.64

Avacopan (CCX168) is a C5aR antagonist (IC50=0.1 nM) with selective and oral activity. Avacopan blocks the action of C5a and prevents the development of GN induced by anti-myeloperoxidase antibodies in a mouse model of AAV. Avacopan can be used to treat anti-neutrophil cytoplasmic antibody (ANCA)-related vasculitis.

3 years

C(=O)(N1[C@H]([C@@H](C(NC2=CC(C(F)(F)F)=C(C)C=C2)=O)CCC1)C3=CC=C(NC4CCCC4)C=C3)C5=C(C)C=CC=C5F

-20°C

12352200