Avapritinib (Standard)
HY-101561R
Product group Assays
Overview
- SupplierMedChem Express
- Product NameAvapritinib (Standard) [1703793-34-3]
- Delivery Days Customer5
- CertificationResearch Use Only
- Scientific DescriptionAvapritinib (Standard) is the analytical standard of Avapritinib. This product is intended for research and analytical applications. Avapritinib (BLU-285) is a highly potent, selective, and orally active KIT and PDGFRA activation loop mutant kinases inhibitor with IC 50 s of 0.27 and 0.24 nM for KIT D816V and PDGFRA D842V , respectively. Avapritinib (BLU-285) binds the active conformation of the kinase and shows antitumor activity. Avapritinib (BLU-285) attenuates the transport function of both ABCB1 and ABCG2 [1] [2] .
- UNSPSC41116135