Bio-Connect

Avapritinib (Standard)

HY-101561R
MedChem Express
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Avapritinib (Standard) [1703793-34-3]
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Scientific Description
    Avapritinib (Standard) is the analytical standard of Avapritinib. This product is intended for research and analytical applications. Avapritinib (BLU-285) is a highly potent, selective, and orally active KIT and PDGFRA activation loop mutant kinases inhibitor with IC 50 s of 0.27 and 0.24 nM for KIT D816V and PDGFRA D842V , respectively. Avapritinib (BLU-285) binds the active conformation of the kinase and shows antitumor activity. Avapritinib (BLU-285) attenuates the transport function of both ABCB1 and ABCG2 [1] [2] .
  • UNSPSC
    41116135