Avatrombopag

AbMole BioScience

Avatrombopag

9

570406-98-3

Chemical

Research Use Only

C29H34Cl2N6O3S2

649.65

Avatrombopag (AKR-501) is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist (EC50=3.3 nM). Avatrombopag mimics the biological activities of TPO. Avatrombopag increases platelet production by activating the intracellular signaling system.

OC(=O)C1CCN(CC1)C2=C(Cl)C=C(C=N2)C(=O)NC3=NC(=C(S3)N4CCN(CC4)C5CCCCC5)C6=CC(=CS6)Cl

12352200