Avatrombopag (Standard) [570406-98-3]
HY-13463R
Product group Assays
Overview
- SupplierMedChem Express
- Product NameAvatrombopag (Standard) [570406-98-3]
- Delivery Days Customer5
- CAS Number570406-98-3
- CertificationResearch Use Only
- Molecular FormulaC29H34Cl2N6O3S2
- Molecular Weight649.65
- Scientific DescriptionAvatrombopag (Standard) is the analytical standard of Avatrombopag. This product is intended for research and analytical applications. Avatrombopag (AKR-501) is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist (EC50=3.3 nM). Avatrombopag mimics the biological activities of TPO. Avatrombopag increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A[1][2][3].
- SMILESO=C(C1CCN(C2=NC=C(C(NC3=NC(C4=CC(Cl)=CS4)=C(N5CCN(C6CCCCC6)CC5)S3)=O)C=C2Cl)CC1)O
- UNSPSC41116135