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ProductsBack/AVEN Polyclonal Antibody

Western blot analysis of extracts of various cell lines using AVEN Polyclonal Antibody at dilution of 1:3000.

Western blot analysis of extracts of various cell lines using AVEN Polyclonal Antibody at dilution of 1:3000.

Western blot analysis of extracts of various cell lines using AVEN Polyclonal Antibody at dilution of 1:3000.

AVEN Polyclonal Antibody

E-AB-64372

Product group Antibodies

Overview

Supplier
Elabscience
Product Name
AVEN Polyclonal Antibody
Delivery Days Customer
12
Certification
Research Use Only
Scientific Description
AVEN, a cell death regulator, is an important signal inducer in acute leuke-mias. AVEN is a highly conserved peripheral membrane protein that protects the cell against the proteolytic activation of caspases as well as Apaf-1 mediated apoptosis by interfering with Apaf-1s ability to self-associate. Bcl-2 and Bad also interact with AVEN to prevent apoptosis. AVEN is highly expressed in ovary, heart, thymus, spleen, testis and colon, but can also be detected in other tissues. Erythropoietin and methylprednisolone may play important roles in the expression of AVEN in cardiac tissue, especially after a traumatic brain injury. In young patients suffering from acute lymphoblastic leukemia (ALL), AVEN expression may be a useful tool in prognosis prediction.
UNSPSC
12352203

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