AWZ1066S [2239272-16-1]

MedChem Express

AWZ1066S [2239272-16-1]

10

2239272-16-1

Research Use Only

98.65

C19H19F3N6O

404.39

AWZ1066S is a highly potent, specific and orally active anti-Wolbachia agent with EC50 value of 121 nM. AWZ1066S also is a weak CYP2C9 inhibitor and a weak CYP3A4 inducer with IC50 values of 9.7 microM and 37 uM, respectively. AWZ1066S can be used for the research of tropical diseases such as Onchocerciasis (river blindness) and lymphatic filariasis (elephantiasis) [1].

C[C@@H](COCC1)N1C2=NC3=C(C=CC=N3)C(NCC4=CC=CN=C4C(F)(F)F)=N2

-20°C,2°C to 8°C

12352200