
Immunohistochemical analysis of paraffin-embedded CL1-5 xenograft, using AXL(GTX101345) antibody at 1:200 dilution.
Antigen Retrieval: Trilogy? (EDTA based, pH 8.0) buffer, 15min
AXL antibody [C2C3], C-term
GTX101345
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetAXL
Overview
- SupplierGeneTex
- Product NameAXL antibody [C2C3], C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.34 mg/ml
- ConjugateUnconjugated
- Gene ID558
- Target nameAXL
- Target descriptionAXL receptor tyrosine kinase
- Target synonymsARK, AXL3, JTK11, Tyro7, UFO, tyrosine-protein kinase receptor UFO, AXL oncogene, AXL transforming sequence/gene
- HostRabbit
- IsotypeIgG
- Protein IDP30530
- Protein NameTyrosine-protein kinase receptor UFO
- Scientific DescriptionThe protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Tsai LH, Wu JY, Cheng YW, et al. The MZF1/c-MYC axis mediates lung adenocarcinoma progression caused by wild-type lkb1 loss. Oncogene. 2015,34(13):1641-9. doi: 10.1038/onc.2014.118Read this paper

![Non-transfected (–) and transfected (+) HeLa whole cell extracts (60 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with AXL antibody [C2C3], C-term (GTX101345) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Non-transfected (–) and transfected (+) HeLa whole cell extracts (60 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with AXL antibody [C2C3], C-term (GTX101345) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX101345/GTX101345_39812_20180907_WB_shRNA_watermark_w_23060100_198.webp)






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![WB analysis of truncated Trx-AXL recombinant protein (1) using GTX83181 AXL antibody [1B3A2].](https://www.genetex.com/upload/website/prouct_img/normal/GTX83181/GTX83181_20170912_WB_w_23061322_890.webp)